Pigment Dispersion Syndrome

Pigment dispersion syndrome is a condition in which pigment rubs off the back of the iris and circulates inside the eye, where it can block drainage and raise the risk of glaucoma.

Common symptoms

Often none in early stages, but some people notice intermittent blurred vision, halos around lights, or aching, especially after exercise.

Description

In pigment dispersion syndrome, movement of the iris causes it to rub against the fibres that hold the lens in place. Pigment granules are released and carried by the fluid inside the eye, where they can settle on the cornea, the lens, and the drainage structures.

The condition is most common in young, short-sighted adults, particularly men. Over time, pigment blocking the drainage angle can raise pressure inside the eye and lead to pigmentary glaucoma, which can cause gradual loss of side vision if left untreated.

Management depends on eye pressure and nerve health. Options range from monitoring, to eye drops, to laser treatments such as peripheral iridotomy, which can reduce further pigment release. People with the condition are advised to have regular eye checks throughout life.