Pseudoexfoliation Syndrome

Pseudoexfoliation syndrome is a common age-related condition in which a flaky material builds up on structures within the eye, increasing the risk of glaucoma and complications during cataract surgery.

Common symptoms

Often none at first, but some people notice gradual loss of side vision from associated glaucoma, and the condition can cause visual symptoms from early cataract formation.

Description

Pseudoexfoliation syndrome causes a dandruff-like material to deposit on the lens, iris, and drainage structures of the eye. Although the cause is not fully understood, it is more common with increasing age and has a genetic link.

The main concern is pseudoexfoliation glaucoma, where the flaky material clogs the eye's drainage system and raises pressure inside the eye. This form of glaucoma can progress more quickly than typical open-angle glaucoma and often needs closer monitoring and earlier treatment.

Management focuses on regular eye pressure checks and treating glaucoma if it develops, using drops, laser, or surgery. Cataract surgery in people with pseudoexfoliation can be more challenging because the supporting fibres of the lens are often weakened, so surgeons plan carefully in advance.